Chronic Infection with hepatitis C virus can increase the risk of Parkinson’s disease to around 30% ‒ this is a conclusion of the authors of the research carried out in Medical University of China and published in Neurology magazine.
As the years go by, more and more people are struggling with allergic rhinitis. Permanent rhinorrhoea, sneezing or nasal congestion caused by inflammation of nasal mucosa are the reasons of common use of variety of pharmacological substances which are available in the drug stores. None of the groups of medicines which are currently used during treatment of rhinitis – steroids, antihistamines, antileukotrienes, immunotherapy etc., doesn’t cure it completely, so search for something more effective is still in process. Read full text »
Scientists from University of Toronto in Canada conducted a systematic review of the studies which evaluated the impact of regular training for adults infected with HIV. The article published in April 2016 has been created by using Cochrane Collaboration protocol.
Melanoma originates from pigment cells – melanocytes. Melanoma is the main cause of deaths of skin neoplasms. It is one of the most refractory neoplasms. Many scientific reports indicate the possibility of using the virus as a weapon against cancer, especially in inoperable cases. Read full text »
Multiple myeloma (MM) is considered to be an incurable disease. However, with the release of Daratumumab by the US FDA in November 2015 there is a real hope for patients suffering from this chronic disease. The drug was registered for patients with MM in whom the use of elementary line treatment, with the proteasome inhibitor (PI) and an immunomodulating agent, was ineffective.
Since the last several months there is more new information about the risk of complications connected with Zika virus infection, especially for pregnant women. Zika virus is a member of Flaviviridia e family and is spread by some species of mosquitoes of the Aedes genus. Read full text »
Osteoporosis is a generalized metabolic bone disease, characterized by low bone mass, impaired microarchitecture of the bone tissue and consequently the increased susceptibility to fracture. It occurs most frequently in women after menopause (postmenopausal osteoporosis). The bones undergo remodeling throughout life. Two processes are responsible for their density – bone resorption stimulated by osteoclasts and bone formation performed by osteoblasts. This fact made these cells the main goal of pharmacotherapy for osteoporosis. Read full text »
Blood-brain barrier (BBB) has always posed a challenge for pharmacology. So far, there is no completely effective method to administrate peptide drugs, antibiotics and chemotherapeutic agents through the BBB (intrathecal injections are the alternative). The development of an effective penetration method through the blood-brain barrier would open new possibilities in the treatment of central nervous system (CNS) diseases with peptide drugs. Anand P et al. hit upon an innovative idea to overcome this problem. They used specially modified bacteriophages as nanocontainers full of painkillers, which allowed the application of the substance in the target area of action.