Pathology videos
Bone - Osteosarcoma
Like any sarcoma, what organ is this tumor most likely to metastasize to first? Why, anatomically speaking?
Bone - Multiple Myeloma
Find sheets of mostly normal looking plasma cells. Should a normal marrow ever have sheets of plasma cells? What is the normal acceptable percantage of marrow plasma cells? What is a monoclonal gammopathy?...
Bone - Fibrous Dysplasia
Does the fibrous or the interspicular component of this tissue appear overgrown? Do the spicules, conversely, look thinner than usual? Show, i.e., dileanate a fibrous area between spicules? Is this dysplastic...
Bone - Chondroma
Does a chondroma look like rather normal cartilage histologically? Is this benign? If it wasn't benign, might it still look like normal cartilage? Demonstrate lacunar crowding. How many condrocytes should...
Blood - Chronic Myelogenous Leukemia
Which of the three cell lines are classically elevated in this disease, RBC, WBC, platelets, or all? What percentage of the myeloid series cells in this smear do you estimate to be blasts? Can this turn...
Blood - Acute Leukemia
Find an absolutely indisputable blast cell, and describe. in words, why it is a blast. Does the correct identification of ANY TRUE blast cell in a peripheral smear present suspicion for a leukemia?
Blood - Chronic Lymphocytic Leukemia
What does a sustained peripheral smear lymphocyte count have to be in an adult over 50 to warrant the diagnosis of CLL? Do you need a bone marrow puncture to make this diagnosis? Are these calls blasts...
Bladder - Urothelial Carcinoma Grade III
Why is this classified as Grade III? Is a higher grade more likely to look worse and behave worse? Show bladder wall (i.e., smooth muscle) invasion. Can the words invasion and infiltration be used interchangeably?
Bladder - Urothelial Carcinoma Grade I
Why is this called Grade I? Does it invade the smooth muscle of the bladder wall?
Bladder - Urothelial Carcinoma (Transitional...
Find an area of CIS. Is it associated with considerable underlying inflammation? Does inflammation cause cancer?
Adrenal - Pheochromocytoma
Why are these often called the most malignant looking benign tumors in pathology? Does the cortex look normal? Could this produce a curable type of hypertension? What is the diagnostic lab/physiologic...
Adrenal - Nodular Hyperplasia
Find a nodule. Could this be functional? Can you tell it is functional just from the histology or would you need to measure hormone levels? What is another way you could tell it is functional without...
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