Histologically, epidermal cysts are lined with a true squamous epithelium similar to that seen on the surface of the skin. The cyst itself is filled with laminated layers of shed keratin.
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![Epidermal Cyst [surgical specimen]](https://medtube.net/images/min/682d3e9584f601fc595604bcdf1a1f66/149/112/1 "Epidermal Cyst [surgical specimen]")