The prolapsed mass seen at the colonoscopy Benign or malignant? Once a lesion is recognized and its size determined, the decision that must be made is whether or not the polyp is benign or malignant. There are few criteria that can be used to make the determination if any particular colonic lesion is malignant. A question that arises is whether or not to perform a biopsy and bring a patient back for polypectomy based on the subsequent results of biopsy or to depend on the visual impression of whether or not the polyp is benign.
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