An 85 year-old female two years ago, she underwent open cholecystectomy. The patient complained of epigastric discomfort, an upper video gastroscopy was performed. A deformed antrum was appreciated, biliar reflux is observed, biopsies where taken to rule out carcinoma. Intestinal metaplasia is the most dramatic epithelial transformation, the acquisition of the epithelium that is normally observed only in the intestine. Intestinal metaplasia has not only morphologic and biochemical properties of the small intestinal epithelium but also functional ones. The metaplastic stomach changes from a secretory organ to an “intestinal” organ capable of the absorption of certain substances such as lipid, from the gastric lumen.
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