Flexible Endoscopic Suturing - End of The Gastroplication

The gastroplication has been completed. Plication techniques create a mechanical barrier to reflux through apposition of 2 mucosal surfaces at the gastroesophageal junction or in the cardia. The mechanisms as to how endoscopic suturing might improve competence of the gastroesophageal junction, however, remain unclear. The manometric studies that are available are conflicting. Some have reported an increase in basal lower esophageal sphincter (LES) pressure and length. A multicenter study, however, found no impact on sample measures of LES function in reflux disease patients despite evidence of symptom benefit.