Lower Esophageal (Schatzki) Ring. With symptomatic Schatzki ring had the evidence of significant gastroesophageal reflux either on endoscopy or ambulatory 24-h esophageal ph monitoring. Pathophysiology: The pathogenesis of Schatzki rings is not clear, and at least 4 hypotheses have been proposed. These hypotheses may not be mutually exclusive. Proposed hypotheses are as follows: 1. The ring is a pleat of redundant mucosa that forms when the esophagus shortens transiently or permanently for unknown reasons. 2 The ring is congenital in origin. 3.The ring is actually a short peptic stricture occurring as a consequence of gastroesophageal reflux disease. 4.The ring is a consequence of pill-induced esophagitis.
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