Intestinal hemorrhage due to a typhoid fever. The ileocecal valve and the terminal ileum are seen in the video clip. There are several tiny and bleeding ulcers. Invasion of Peyer patches occurs during either the primary intestinal infection or secondary bacteremia, and further seeding occurs through infected bile. The Peyer patches become hyperplastic with infiltration of chronically inflamed cells, which may lead to necrosis of the superficial layer and ulcer formation, with potential hemorrhage from blood vessel erosion or peritonitis from transmural perforation.
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