Crohn´s Disease Of The Ileocecal Valve And Terminal Ileum (5 of 5)

Fistula formation is common and can cause indolent abscess, malabsorption, cutaneous fistula, persistent urinary tract infection, or pneumaturia. Although uncommon, free intestinal perforation can occur as a result of transmural involvement of the disease. Extraintestinal manifestation of Crohn disease includes oral aphthous ulcer, erythema nodosum, osteomalacia, and anemia due to chronic malabsorption; osteonecrosis due to chronic steroid therapy; gallstone formation due to ileal involvement of disease leading to poor bile salt reabsorption; oxalate kidney stones due to colonic disease; pancreatitis due to sulfasalazine, mesalamine, azathioprine, or 6-mercaptopurine therapy; bacteria overgrowth due to surgical resection; and miscellaneous manifestations such as amyloidosis, thromboembolic complications, hepatobiliary disease, and primary sclerosing cholangitis.