Endoscopy of Severe Ulcerative Colitis Severe colitis noted during colonoscopy. The mucosa is grossly denuded and multiple pseudopolyps. Extensive colitis (pancolitis) is diagnosed when inflammation extends into the transverse or right colon. In this setting patients are more likely to present with diarrhea as a result of the diminished absorptive capacity of the colon, accompanied by rectal bleeding, urgency and tenesmus. Cramping abdominal pain may be diffuse or localized, and patients are more likely to have weight loss, systemic or extraintestinal symptoms, and anemia.
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