Conceptually, cyanoacrylate glue provides an ideal endoscopic treatment for gastric varices. Native cyanoacrylate is a liquid with a consistency similar to water and therefore lends itself to intravariceal injection. When added to a physiologic medium such as blood, the cyanoacrylate rapidly polymerizes, forming a hard substance. Thus, after injection into a varix, the cyanoacrylate plugs the lumen. This results not only in rapid hemostasis in cases of active bleeding, but it also prevents the recurrence of bleeding from the treated varix
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