Dieulafoy´s Lesion (Exulceratio Simplex) Dieulafoy´s Lesion is a vascular abnormality found almost exclusively in the proximal stomach that presents dramatically as acute and rapidly recurrent massive upper gastrointestinal hemorrhage when a small sub mucosal artery ruptures into the gastric lumen. Hemorrhage is caused by thrombosis and perforation of an abnormally large, tortuous sub mucosal artery in the center of a solitary 2- to 5-mm gastric mucosal erosion, surrounded by normal-appearing mucosa.
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