Diffuse nodular thickening of the gastric folds Linitis plastica is a diffuse infiltrative gastric adenocarcinoma. This condition is marked by thickening and Deeper biopsy from the same nodule confirming the presence of independent cells in the submucosa. fibrosis of the gastric wall, the malignant cells being scarcely distributed in the fibrous stroma. Frequently the gastric mucosa is spared of malignant invasion, making an endoscopic diagnosis very difficult. The most common site of gastric linitis is the antral and pyloric regions (with variable spread proximally towards the gastric body) The fundus is least often involved. Our patient’s main complaint was progressive dysphagia. The pericardial gastric folds viewed in endoscopy were probably associated with local extension of the adenocarcinoma and responsible for the clinical manifestations.
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