Is evident by the presence of ulcerations. The following factors or conditions may increase risk of reflux esophagitis: Pregnancy Obesity Scleroderma Smoking, Alcohol, coffee, chocolate, fatty or spicy foods Certain medications (eg, beta-blockers, nonsteroidal anti-inflammatory drugs [NSAIDs], theophylline, nitrates, alendronate, calcium channel blockers) Mental retardation requiring. institutionalization. Spinal cord injury. Immunocompromised patients. Radiation therapy for chest tumors. Pill esophagitis, thought to be secondary to chemical irritation of esophageal mucosa from certain medications (eg, iron, potassium, quinidine, aspirin, steroids, tetracyclines, NSAIDs), especially when swallowed with too little fluid.
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