Multiple tiny 1 mm. vascular lesions at the jejuno Telangiectases in the gastric mucosa of a patient with Osler-Weber-Rendu syndrome. The lesions can be seen most prominently at the 11-o'clock position proximally. The endoscopic evidence of vascular lesions in patients with bleeding confirms the role of GI telangiectasias in the bleeding episodes. The researchers do not, however, address the more frequent scenario of occult GI blood loss that occurs without melena or hematemesis, and they may have underestimated the role of GI lesions in HHT anemia.
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