Ameboma (amebic granuloma) is a localized thickening of the intestinal wall about an ulceration caused by Endamoeba histolytica which results in a lesion capable of being mistaken for a neoplasm because of the associated narrowing of the intestinal lumen and presence of a palpable mass. Amebiasis is uncommon in developed countries. Its clinical presentation can be variable and non-specific, and the diagnosis can be easily overlooked. Among the wide variety of clinicopathologic manifestations of the intestinal amebiasis, amebomas occur rarely, resulting from the formation of annular colonic granulation tissue, usually in the cecum or ascending colon.
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