Schistosoma Mansoni in the Cecum (2 of 9)

High Magnification Image and Video Clip. The Schistosome Egg is Responsible For Most of the Pathology Associated with Schistosomiasis. Schistosome eggs, which may become lodged within the hosts tissues, are the major cause of pathology in schistosomiasis, which takes a number of forms. Onset of egg laying in humans is sometimes associated with an onset of fever (Katayama fever) This "Acute Schistosomiasis" is not however as important as the chronic forms of the disease. For S. mansoni and S. japonicum these are "Intestinal" and "Hepatic Schistosomiasis", associated with formation of granulomas around trapped eggs lodged in the intestinal wall or in the liver respectively. The hepatic form of the disease is the most important, granulomas here giving rise fibrosis of the liver and hepatosplenomegaly in severe cases