Early Gastric Cancer of the Gastroesophageal Junction - Injection of Solutions to Perform the Mucosectomy

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15 years ago
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specialty:
Gastroenterology

Case description

Saline dextrosa 50% and adrenalin 1/100.000 was injected into the submucosa. Traditionally, Barrett's esophagus was defined as the presence of columnar mucosa extending >/= 3 cm into the tubular esophagus. This definition has evolved into the presence of any specialized columnar epithelium in the esophagus as it became known that the presence of intestinal metaplasia of any length was associated with an increased risk of esophageal adenocarcinoma. Barrett's esophagus was simply referred to as short-segment (< 3 cm) or long-segment (>/= 3 cm) Even this definition became problematic when it was discovered that as many as 1 in 5 Barrett's esophagus patients have this specific epithelium in the region of an otherwise normal-appearing squamocolumnar junction (ie, intestinal metaplasia of the gastric cardia) While this latter lesion is of little clinical relevance (as neither dysplasia nor cancer occurs to be appreciably increased in that setting), cancer and dysplasia do occur in the more numerous short-segment Barrett's esophagus patients as well as the less commonly encountered long-segment Barrett's patients. While the long-segment patients likely have greater risk for neoplasia compared with the short-segment patients, the risk in short-segment cases is still increased over that of the general population. Whether surveillance exams should be at different intervals for these 2 classifications of Barrett's based on length is controversial, and current guidelines treat them identically.

tags: Adenocarcinoma endoscopy mucosectomy

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