The inflammatory infiltrate from patients with SLE was found to contain higher levels of young and mature fibroblasts than those from patients with gastroduodenitis, and was associated with the progression of SLE. During disease exacerbation, immune complex deposition was observed in the arteriolar walls The inflammatory changes in the gastric and duodenal mucosa were ascertained to be associated with the progression of SLE. In exacerbation of SLE, the walls of vessels (arterioles) exhibited immune complexes classified mainly as IgG and, to a lesser degree, as IgM. In remission, the luminescence of the vessels decreased. The serum level of immunoglobins did not correlate with their regional production in the gastric and duodenal mucosa.
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