Gastric Erosion is observed the biopsies were negative to malignancy. Gastrointestinal (GI) manifestations are common in patients with systemic lupus erythematosus (SLE) Virtually all patients with SLE require treatment with NSAID therapy and/or corticosteroids The ulcerogenic effects of NSAIDs and corticosteroids used in combination are synergistic and put the patient at a high risk of serious ulcer disease. In addition, high-dose steroids may mask the early clinical signs of peptic ulcer perforation.
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