The long-term relapse rate of non-neoplastic BE following complete ablation with high-power APC is low. APC is a method of contact-free high-frequency current coagulation in which the burning of tissue stops as soon as the area is ablated. One recent study using high-power APC was reported to result in complete restoration of squamous mucosa in 33 out of 33 patients after a mean of 1.96 sessions. The major complication was chest pain and odynophagia, which occurred in 57.5% of patients and lasted 3-10 days. Only 3 patients experienced stricture, which was treated easily with dilation. Other studies have been less encouraging, with persistence of residual foci of Barrett epithelium under the neosquamous lining in 22-29%, and deep esophageal ulceration with massive bleeding.
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