RRP-Recurrent Respiratory Papillomatosis

Usually it is human papillomavirus (HPV) of subtypes 6 and 11 which causes a laryngeal papillomatosis. The most common symptoms are: hoarseness or manifestations of an airway obstruction. The juvenile type are generally more aggressive and requires more frequent surgical intervention to relief the airway, as compared to the adult onset. It is treated by periodic removal and amongst surgical techniques currently being employed include carbon dioxide or pulse-dye lasers, microdebrider, and the use of microsurgical instruments. In selected cases, antiviral agent like cidofovir and interferon therapy are indicated. The disease might go into remission in some cases. On the other hand, more distal involvement is possible and there is a risk of malignant transformation into squamous cell carcinoma in long-standing cases. In this video we can see laryngeal papillomatosis in an adult which has involved both the true and false vocal cords bilaterally. The significant voice change had been caused with stridor which needs surgical removal by using carbon dioxide laser.