This 65 year-old female, without a significant medical history presented with rectal bleeding, with the digital examination a hard mass was palpable at 8 cm. of the anal verge. Analysis showed it was a rectal GIST, a rare mesenchymal tumor of the gastrointestinal tract, which expressed CD117 (or c-kit, a marker of kit-receptor tyrosine kinase) and CD34.
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