Chromoendoscopy with indigo carmin. Cap polyposis is characterized by rectosigmoid polyps that have tortuous elongated crypts and are covered by a cap of fibropurulent exudate. The pathogenesis is unknown, but the histology suggests that mucosal prolapse may play a role. The current therapy often used for inflammatory bowel diseases has frequently been ineffective. Overall, infliximab lead to symptomatic improvement and histologic resolution of the polyps.
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