More Slices Remove a larger polyp en bloc to facilitate histologic analysis. Large sessile polyps may require piecemeal resection in 1- to 2-cm segments, although if submucosal saline injection is employed, and there is a sufficient saline cushion to prevent thermal damage to the muscularis propria, I prefer to remove a larger polyp en bloc to facilitate histologic analysis (particularly in the unanticipated event of a malignant polyp).
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