Diverticular Colitis Infrequently, patients with diverticular disease develop a segmental colitis most commonly in the sigmoid colon. The endoscopic and histologic features vary, ranging from mild inflammatory changes with submucosal hemorrhages (peridiverticular red spots on colonoscopy sometimes referred to as "Fawaz spots") to florid, chronic active inflammation resembling (histologically and endoscopically) inflammatory bowel disease The pathogenesis is incompletely understood. The cause may be multifactorial, related to mucosal prolapse, fecal stasis, or localized ischemia.
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