Colorectal carcinoma develops over a long period of time with an estimated doubling time of almost two years • Presenting symptoms are related to chronic blood loss with the signs and symptoms of iron deficiency anemia, increasing luminal obstruction with change in bowel habits, diameter of stool, variable constipation, diarrhea, and vague abdominal discomfort or pain. A palpable mass lesion is a late finding • Right sided tumors are most associated with blood loss and rarely with obstruction while left sided lesions present with signs of obstruction. • Treatment is surgical and prognosis is related to stage at presentation. • About 25% of patients will present with metastatic disease, primarily lymph nodes and liver. The overall survival is 50%.
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