Lateral view of this submucosal tumor. The classic or usual GI tract GIST has a similar morphologic appearance to leiomyomas in other organs. In the gut, they are usually small, and well circumscribed. The tumors typically arise from the muscularis propria; growth may be intraluminal, extraluminal, or a combination with a dumb-bell shape. GIST can range in size from less than 0.5 cm (microgist) to as large as 30 cm.
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