Chromatoscopy with lugol´s stain. A leather bottle stomach - linitis plastica - describes a stomach that has a gastric carcinoma which is morphologically an infiltrating carcinoma. Linitis plastica may show very little mucosal lesions on gross appearance. As a rule, since macroscopic features do not often permit the distinction between benign and malignant lesions, multiple endoscopic biopsies are required. However, standard endoscopic biopsy specimens which usually contain only mucosa offer frequently negative results for malignancy.
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