Tetracyclines are the most common antibiotics to induce esophagitis, particularly doxycycline Essentially all of the antiinflammatory agents can damage the esophagus; the highest number of reported cases have been with aspirin. The major offenders in the "other" category include potassium chloride, quinidine preparations, and iron compounds in the United States; emepronium, alprenolol, and pinaverium are common etiologies in other countries. In addition, the bisphosphonate alendronate has the potential to be a cause because of its increasing use for the treatment of osteoporosis and other disorders
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