patomorphology

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Skin- Leukocytoclastic Vasculitis

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Define the word leukocytoclasis. Show an example from this slide.

Lung, Lymph Node - Asthma

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Find necrosis, find mucous plugs, find smooth muscle hypertrophy, find eosinophil infiltrates. Which 2 common disease states are associated with a peripheral eosinophilia?

Lung - Wegener Granulomatosis

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Find necrosis. Find vasculitis. Find granulomas. Find multinucleated giant cells. What is the mortality of this disease? High?

Lung - Asthma

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Describe, in words, some major ways bronchioles in asthma differ from normal bronchioles. Show some.

Liver - Amyloidosis

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Name at least three other things which appear hyaline on microscopy, i.e., eosinophilic, glassy, and amorphous, besides amyloid?

Liver - Primary Biliary Cirrhosis

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What two histopathologic features seen here prove this is cirrhosis? In which part of the hepatic lobule are the early inflammatory and fibrotic changes the most severe in primary biliary cirrhosis? Portal...

Kidney - Systemic Lupus Erythematosus

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Can you agree that the glomerular basement membrane area is thickened, compared to a normal glomerulus? Find a wire loop Are there many different kinds of renal pathologies with lupus, or is this the...

Kidney - Chronic Transplant Rejection

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What are the three classic patterns of transplant rejection, with respect to time after transplant? Which histopathologic pattern is present here. Show it, and verbalize it.

Kidney - Amyloidosis

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Find a hyalinized area in a blood vessel. Find one in a blood vessel. How would you prove this is amyloid? How does it differ from an atherosclerotic plaque? How does it differ from a thrombus?

Kidney - Microscopic Polyarteritis

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Encircle an involved blood vessel. What kind of blood vessel is it? Described the abnormality in plain English.

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