patomorphology

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Hashimoto Thyroiditis

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Find several secondary lymphoid follicles (i.e., lymphoid nodules). Is the presence of many secondary lymphoid follicles in the thyroid fairly diagnostic of Hashimoto thyroiditis? Is Hashimoto thyroiditis...

Thyroid - Graves Disease

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Show scalloping at the periphery of the colloid. Is this regarded as fairly diagnostic of hyperthyroidism? What are the three classic findings of Graves disease?

Temporal Arteritis

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What is another name for temporal arteritis? What is the proper name of this artery? Superficial or deep temporal? Is it easy to biopsy because of its size, location, and abundant collaterals? Find some...

Stomach - Chronic Gastritis

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Why would an inflammation of the stomach cause an anemia with large RBC's, i.e., macrocytes? Find a chronically inflamed area? What are 90Andpercnt; of the cells

Stomach - Atrophic Gastritis

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Find some chronic gastritis. Why is this also called atrophic? Is there mucosal atrophy? What common gastric mucosal products are decreased in this disease?

Spleen - Amyloidosis

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What percentage of this spleen consists of amyloid? What is a sago spleen? Did amyloid get its name because it originally was noticed to have the staining properties of starch? Is amyloid starch?

Small Intestine - Rheumatoid Vasculitis

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Find (encircle) a large artery with vasculitis. Describe it in your own words.

Small Intestine - Celiac Sprue

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Why doesn't the mucosa have fingerlike villi like it should have in the small bowel? Are there increased cells in the lamina propria? What kind?

Skin, Kidney - Systemic Sclerosis (Scleroderma)

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Find atrophy (epidermis) and fibrosis (dermis) of skin. Find thickening in the intima of the kidney.

Skin - Rheumatoid Nodule

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Can this be regarded as a granuloma also? Find necrosis and histiocytes. Are these often seen in RA? Are they very often not associated with joints at all? If you see one, does that mean the patient must...

Skin- Leukocytoclastic Vasculitis

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Define the word leukocytoclasis. Show an example from this slide.

Lung, Lymph Node - Asthma

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Find necrosis, find mucous plugs, find smooth muscle hypertrophy, find eosinophil infiltrates. Which 2 common disease states are associated with a peripheral eosinophilia?

Lung - Wegener Granulomatosis

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Find necrosis. Find vasculitis. Find granulomas. Find multinucleated giant cells. What is the mortality of this disease? High?

Lung - Asthma

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Describe, in words, some major ways bronchioles in asthma differ from normal bronchioles. Show some.

Liver - Amyloidosis

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Name at least three other things which appear hyaline on microscopy, i.e., eosinophilic, glassy, and amorphous, besides amyloid?

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