Current evidence suggests that laparoscopic fundoplication is more effective than medical therapy for the short- and medium-term treatment of gastroesophageal reflux disease. In contrast to medical therapy that inhibits only acid reflux, antireflux surgery is designed to prevent reflux of all gastric content. This is achieved by creating a mechanical antireflux valve that increases lower esophageal sphincter pressure and markedly reduces the rate of spontaneous transient relaxations accompanied by reflux.
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