Seen after staining with methylene blue. Tuberculosis.--M tuberculosis is the most common cause of serious HIV-related infection worldwide, although it is less common in the United States than in other countries. About 43% of HIV-infected persons develop tuberculosis in developing countries , whereas only 4% develop tuberculosis in the United States. Tuberculosis in HIV-infected patients tends to occur earlier than other AIDS-defining opportunistic infections, usually when the patient's CD4 cell count is in the range of 150 350 cells per microliter.
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