The typical ulcers and redness are seen. Invasive amebiasis due to E. histolytica is more common in developing countries. In areas of endemic infection, a variety of conditions including ignorance, poverty, overcrowding, inadequate and contaminated water supplies, and poor sanitation favor direct fecal-oral transmission of amebas from one person to another. Being responsible for approximately 70 thousand deaths annually, amebiasis is the fourth leading cause of death due to a protozoan infection after malaria, Chagas' disease, and leishmaniasis and the third cause of morbidity in this organism group after malaria and trichomoniasis, according to recent World Health Organization estimates
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