Image of Typical Pseudomembranes The frequency of pseudomembranous colitis with potential fatal outcome is underestimated especially in elderly patients. Proton pump inhibitors appear to increase the risk of acquiring CDC by reducing the acid concentration in the stomach and allowing the organism to pass unharmed into the intestine. Patient-to-patient transmission increases the risk of acquiring CDC. Patients with an infected roommate are more likely to get CDC than patients without an infected roommate. Transmission of infection by hospital personnel contaminated with C. difficile is possible but preventable by using disposable gloves and washing hands thoroughly after examining patients
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