Colon Angiodysplasia (1 of 24)

This is a 63 year-old male, previously admitted on 4 different occasions for massive lower gastrointestinal bleeding, needing multiple blood transfusions. He is referred to our unit for evaluation. Findings included multiple arterial malformations compatible with cecal Angiodysplasia. Sessions with argon plasma coagulation were initiated. 10 days after therapy patient presents with a new episode of massive lower gastrointestinal bleeding, again requiring multiple blood transfusions. New colonoscopy revealed ulcerated nodules in ascending colon not visualized on previous colonoscopy, raising clinical suspicion of a paraneoplasic syndrome. Chest, abdominal, and pelvic CT were normal. Alcaline phosphatase and serum creatinine levels were normal. During the night, a sudden jerk of the left arm produced a pathological fracture of the left humerus. Pictures below.