Symptoms depend on the location of the primary tumor. Cancers of the cecum and ascending colon usually grow larger than left-sided tumors before symptoms occur. Fatigue, shortness of breath, and angina resulting from microcytic hypochromic anemia are common presenting features. Vague abdominal discomfort or a palpable mass may occur later, but obstruction is uncommon (unless the ileocecal junction is involved) because of the larger diameters of the cecum and ascending colon.
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