After malaria, schistosomiasis is the second most prevalent tropical disease in the world. In some parts of the world, it also is known as bilharzia in honor of Theodore Bilharz. He first identified the etiological agent for Schistosoma hematobium in Egypt in 1851. The pathophysiology of schistosomiasis is due to the immune response against the schistosome eggs. The clinical manifestations depend on the species of parasite, intensity of worm burden, and immunity of the person to the parasite. Recent World Health Organization (WHO) reports estimate that 500-600 million people in 74 tropical and subtropical countries are at risk for schistosomiasis. Over 200 million people in these countries are infected. Of these, 120 million are symptomatic, with 20 million having severe clinical disease.
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