Duodenal Mucosa in Celiac Disease. This video endoscopy sequence shows magnifying endoscopy that displayed the mucosa of the duodenum with flat or absent microvillis. Celiac disease (CD) is a genetic disorder. In people with CD, eating certain types of protein, called gluten, sets off an autoimmune response that causes damage to the small intestine. This, in turn, causes the small intestine to lose its ability to absorb the nutrients found in food, leading to malnutrition and a variety of other complications. The offending protein, gluten, is found in wheat, barley, rye, and to a lesser extent. Characterized by damage to the mucosal lining of the small intestine which is known as villous atrophy. responsible for the malabsorption of nutrients resulting in malnutrition.
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