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Colon Angiodysplasia and Multiple Myeloma (21 of 24)
Case description
Multiple myeloma is the most common primary neoplasm
of the skeletal system. The disease is a malignancy of
plasma cells. Radiologically, multiple destructive lesions
of the skeleton as well as severe demineralization
characterize multiple myeloma. The etiology of the disease
is the monoclonal proliferation of B cells, with a resultant
increase of a single immunoglobulin and its fragments in
the serum and urine. Electrophoretic analysis shows
increased levels of immunoglobulins in the blood as well as
light chains (Bence-Jones protein) in the urine.
of the skeletal system. The disease is a malignancy of
plasma cells. Radiologically, multiple destructive lesions
of the skeleton as well as severe demineralization
characterize multiple myeloma. The etiology of the disease
is the monoclonal proliferation of B cells, with a resultant
increase of a single immunoglobulin and its fragments in
the serum and urine. Electrophoretic analysis shows
increased levels of immunoglobulins in the blood as well as
light chains (Bence-Jones protein) in the urine.
