Gastrointestinal stromal tumors (GISTs) of the esophagus are rare, comprising only about 1% of reported GISTs Gastrointestinal stromal tumors (GISTs) are the most common sarcoma of the gastrointestinal tract, but occur rarely in the esophagus. A 45 year-old male, physician, previously asintomatic, a giant GIST was found at the level of the middle third. Hypomotility of the distal esophagus, hiatal hernias and GERD are common findings. Therefore, evaluation for GERD should be considered before and after surgery for esophageal GIST.
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