Endoscopy of Acute Gastritis Bacterial infections also can cause gastritis. The most common type of infection is caused by H pylori. H pylori gastritis typically starts in the antrum, causing intense inflammation, and over time, it may extend to involve the entire gastric mucosa. It is also responsible for as many as 80% of gastric ulcers and is associated with a transient increase in gastric acid secretion. The acid secretion drops as the corpus of the stomach is involved. Urease produced by Helicobacter Pylori catalyzes the hydrolysis of urea to ammonia and carbon dioxide. Hydroxide ions generated by the equilibration of water with ammonia are hypothesized to contribute to gastric mucosal epithelial damage. Helicobacter Pylori is thought to be spread from person to person via oral-oral and/or fecal-oral routes.
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