Acute Gastritis. Acute gastritis has a number of causes, including certain drugs; alcohol; bacterial, viral, and fungal infections; acute stress (shock); radiation; and direct trauma. Nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, ibuprofen, and naproxen, can be direct irritants and a cause of gastritis. Because of gravity, the irritants lie on the greater curvature of the stomach, and therefore, gastritis and ulcers are seen distally on or near the greater curvature of the stomach. Gastritis can occur even when NSAIDs are taken systemically or when the drugs are ingested persistently or in large quantities. Alcoholic beverages, such as whisky, vodka, and gin, are direct irritants to the stomach and can cause alcoholic gastritis.
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