Watermelon-stomach is a rare cause of gastrointestinal bleeding. There has been an increasing number of reports on the association of this lesion with diseases of the scleroderma group. Gastric antral vascular ectasia (GAVE), also referred to as Watermelon stomach, is a severe haemorrhagic condition that leads to significant morbidity and transfusion dependence in some patients. Re-bleeding following treatment is common, and there are few treatment options. Until recent treatment modalities were developed, the only options available to patients were blood transfusions or the surgical removal of the stomach (antrectomy) The estimated prevalence of GAVE ranges from 0.3 per cent of cases in a large endoscopic series to 4 per cent in highly selected cohorts with severe gastrointestinal bleeding. Although some patients with diffuse GAVE may have portal hypertensive gastropathy, for the purpose of this application the indication is GAVE not related to portal hypertensive gastropathy.
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