Endoscopic views of an ulcerated mid-esophageal squamous cell carcinoma causing lumenal stenosis are seen in the endoscopic image as well as the video clip. Risk factors for esophageal squamous carcinoma include mainly smoking and alcoholism in the U.S. In other parts of the world dietary factors may play a role. Cancer of the esophagus remains a devastating disease because it is usually not detected until it has progressed to an advanced incurable stage. At the time of diagnosis, weight loss and dysphagia are the most common symptoms. Dysphagia usually occurs late in the course of the disease when the esophageal lumen has been narrowed by 50-75%. Less commonly, presenting symptoms may be related to local invasion or metastases
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