Status After Dilatation with Balloon - Endoscopic Assessment

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added:
13 years ago
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specialty:
Gastroenterology

Case description

Status after dilatation with balloon Achalasia is the best understood example of an esophageal motility disorder and characterized by esophageal aperistalsis and impaired relaxation of the lower esophageal sphincter. The histopathology of achalasia involves inflammation of the myenteric plexus of the esophagus with diminution of ganglion cells. Significant reduction in nitric oxide synthase containing neurons has been demonstrated using immunohistochemical staining. Autoimmune, neurodegenerative, and viral etiologies have been implicated in the pathogenesis of achalasia. However, the exact cause has yet to be elucidated. Pharmacologic studies in achalasia patients support the selective loss of inhibitory, nitrergic neurons with preservation of cholinergic innervation.

tags: endoscopy esophagus achalasia balloon dilatation

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