Gastric outlet obstruction (GOO) can result from benign and malignant causes. Surgical gastroenterostomy has been the treatment of choice for patients with benign and malignant GOO with a good functional status. Placement of luminal self-expandable metal stents is currently accepted as the endoscopic treatment of choice for malignant GOO because of its effectiveness and minimally invasive nature. The main limitation of luminal stents is the high incidence of recurrent GOO resulting from tumor/tissue ingrowth/overgrowth. More recently, EUS-guided gastroenterostomy (EUS-GE) has emerged as an alternative to both luminal stent placement and surgical gastroenterostomy.
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