MEDtube Science 2015 - Hypertension, Cardiovascular Episodes And Lipid Profile In Living Kidney Donors In Poland – Single Centre Experience

The long-term risk of hypertension and cardiovascular disease in living kidney donors in Poland remains uncertain. Hypertension is one of the most important causes of cardiovascular disease worldwide. The objective of the study was to evaluate hypertension, cardiovascular disease and lipid profile in living kidney donors after open nephrectomies which were performed between 1995 and 2005 in our institution. Patients and methods. 40 living kidney donors reported for follow-up visit. Donor mean age at a follow-up visit was 46.14 years. Mean observation period was 65.6 months. ABPM was applied to diagnose hypertension after nephrectomy. ECG, cardiac sonography, ophtalmoscopy were performed and lipid profile was assessed. Results. Hypertension was diagnosed in 5% and 30% patients prior to and after nephrectomy, respectively. The difference in frequency of hypertension prior to and after donation was significant (p=0.001). The strongest predictor of hypertension was donor age in regression model. In 5 donors was observed hypertensive angiopathy on ophtalmoscopy. One cardiovascular episode was observed after nephrectomy. Hyperlipidaemia was observed in 7 and 18 donors prior to and after surgery, respectively. The difference in frequency of hyperlipidaemia prior to and after nephrectomy was significant.