Pulmonary Artery Sarcoma Resection and RVOT Reconstruction with Homograft and Dacron

Pulmonary artery sarcoma resection with right ventricular outflow tract (RVOT) reconstruction using a homograft and Dacron graft represents one of the most technically demanding procedures in cardiothoracic oncology. Complete en-bloc resection requires meticulous dissection of the main pulmonary artery and its branches, often under cardiopulmonary bypass, with attention to achieving negative margins while preserving distal pulmonary vasculature. When tumor involvement extends proximally into the pulmonary valve or RVOT, radical excision necessitates reconstruction of the outflow tract. A cryopreserved pulmonary homograft provides a biologically compatible conduit that restores valvular competence and physiologic flow dynamics, while Dacron graft material is frequently used to reconstruct or extend the main or branch pulmonary arteries, ensuring structural durability and tailored sizing. The combination allows restoration of right ventricular–pulmonary arterial continuity, minimizes turbulence and thrombogenicity, and facilitates long-term hemodynamic stability. Given the aggressive nature of pulmonary artery sarcoma, surgical precision, careful margin assessment, and multidisciplinary oncologic coordination remain critical determinants of survival and postoperative functional recovery.